Abstract: In this paper , immunoglobulins were purif ied separetely fr om bile and se rum of un trea ted carp by techniques of sal ting , high speed cent rifugat ion and gel fil tr ation chroma tography(Seph adex G -200), moreover , i ts ant igencitical , chemical and physical character istics were studied .The resul ts indicate that immunoglobul in fr om bile and se rum of carp showed ident ical antigencity , similar chemical and physical char acterist ics . A infer ence would be reasonable that immunoglobulins in different t issues of carp have the same or igin .